clone interdit
- Domaines
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- médecine allergologie
- biologie immunologie
Termes :
- clone interdit n. m.
- clone autoréactif n. m.
Traductions
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anglais
Auteur : Labastrou, Éliane,Définition
A clone of immunocompetent cells reactive to self antigens which, according to the clonal selection theory of immunity, should be eliminated in fetal life. It was suggested that autoimmune disease is caused by such forbidden clones arising by somatic mutation in adult life.
Terme :
- forbidden clone