antigène de classe I
- Domaines
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- médecine allergologie
- biologie immunologie
Termes :
- antigène de classe I n. m.
- CMH de classe n. m.
Traductions
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anglais
Auteur : Labastrou, Éliane,Définition
[Each of] major histocompatibility antigens found on virtually every cell, human erythrocytes being the only notable exception; they are found on molecules consisting of two noncovalently bound chains. One on 44,000-dalton polymorphic glycoprotein partially embedded in the cell membrane, is determined by an MHC gene (HLA-A, -B, or -C in humans); the other, B2-microglobulin, a 12,000-dalton nonpolymorphic protein, is determined by a non-MHC gene. Class I antigens are the classic histocompatibility antigens recognized during graft rejection [...].
Termes :
- class I antigen
- class I MHC molecule